Steroid, Thiamine and Ascorbic Acid for Comatose Out-of-hospital Cardiac Arrest Survivors

Inclusion Criteria: * An out-of-hospital cardiac arrest survivors treated with targeted temperature management (target between 32 and 36 °C) * Presumed cardiogenic cause as cardiac arrest Exclusion Criteria: * \> 12 hours from cardiac arrest to drug or placebo administration * previous poor neurological status (Cerebral Performance Categories 3 to 5) * patients who have set limitations on treatment (e.g. patients with a signed do-not-resuscitate order) * Patients with an underlying terminal-stage disease without an active treatment plan and those who are not expected to survive to discharge * patients taking at least 1 g/day of vitamin C or receiving intravenous thiamine prior to enrolment * patients experiencing cardiac arrest prior to enrolment or who are expected to die within 24 h despite best possible treatment, based on the judgement of medical personnel * pregnant women * patients with glucose-6-phosphate dehydrogenase deficiency * patients with a history of hypersensitivity reactions to the trial drugs * patients with thalassemia * patients with hyperoxaluria * patients with cystinuria * patients with ongoing gout attacks * patients diagnosed with oxalate renal stones * patients who do not voluntarily consent to participate in the trial (directly or by legal proxy).