TerminatedNot Applicable

Parkinson's Disease G2019S LRRK2 Genetic Testing Program

Stopped: Sponsor stopped the study

United States836 participantsStarted 2021-06-08

Plain-language summary

Increase awareness of the G2019S LRRK2 mutation in Parkinson's and no cost genetic testing program.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. Participant must be a person diagnosed with Parkinson's disease who is 18 years or older.
. Participant is under the care of a physician for their Parkinson's disease.
. Participant is able to read, write and understand English, and reside in a country where the shipment of biological samples is allowed.
. Participant is able to grant informed consent.
. In the case of participants, willing to participate in a free genetic testing program to determine if they carry the G2019S LRRK2 mutation.
. Willing to be notified of eligibility for clinical studies (if appropriate).
. Particpants who already believe they have tested positive for the mutation will be allowed to be retested through this program and be notified of potential eligibility for studies.

Exclusion criteria

. Inability to meet any of the inclusion criteria.
. Participant has received on of the following advanced treatments to manage their Parkinson's: gene therapy, deep brain stimulation (DBS), injections into the brain, continuous infusion of medication into their stomach/intestines with a pump.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Identify Parkinson's patients with the G2019S mutation in their LRRK2 gene

Timeframe: 2 years

Trial details

NCT IDNCT04919356

SponsorEscape Bio, Inc.

Sponsor typeINDUSTRY

Study typeOBSERVATIONAL

Primary completion2022-12-05

View on ClinicalTrials.gov More Parkinson's Disease trials