Testing an Herbal Pain Relief Patch to Reduce Pain in Cancer Survivors (NCT04916249) | Clinical Trial Compass
Active — Not RecruitingPhase 2
Testing an Herbal Pain Relief Patch to Reduce Pain in Cancer Survivors
United States68 participantsStarted 2021-05-28
Plain-language summary
The purpose of this study is to find out whether Tibetree Pain Relieving Plaster, an herbal pain relief patch, may be able to reduce this pain. Tibetree Pain Relieving Plaster is available as an over-the-counter (non-prescription) treatment for the temporary relief of minor aches and pains in muscles and joints. This study is the first to test this treatment in people who have had cancer.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age ≥ 18 years or older
* A diagnosis of cancer with no restrictions placed on type of cancer or stage. Eligibility criteria will not be restricted to MSK confirmed biopsy/diagnosis. Participating institution's testing is sufficient for other study sites
* Completed active treatment (surgery, chemotherapy, and/or radiotherapy) at least one month prior to study initiation (patients on continued hormone treatment or maintenance targeted therapies will not be excluded).
* Patients currently have no evidence of disease
* Ambulatory (Karnofsky functional score of ≥ 60)
* Having a focused location of regional musculoskeletal pain (e.g. joints, extremities, back, neck) that can be covered by one patch of PRP
* Worst pain score (numeric pain rating scale) 5 or above in the preceding week
* Pain for at least 3 months and at least 15 days with pain in the preceding 30 days; and willingness to adhere to and understanding of all study-related procedures, including randomization to one of the two possible choices
* Able to understand informed consent and provide signed informed consent form
Exclusion Criteria:
* Patients with non-musculoskeletal pain syndromes (headache, facial pain, chest pain, visceral abdominal pain) will be excluded if these are the sole source of pain but can be present as co-morbid conditions as long as a patient has a primary musculoskeletal pain condition defined as above.
* Patients have generalized musculoskeletal pain such as fibromyalg…
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is testing an herbal pain relief patch specifically in cancer survivors who are in remission — given my current situation, does my doctor think my type of pain and remission status would make me a reasonable candidate to even discuss this study with the research team?
2Since this is a Phase 2 trial, what does that mean for how much is already known about whether the patch is safe and effective, compared to pain treatments I might already be using?
3The trial is actively enrolling but no longer recruiting new participants — does my doctor know if there's a waiting list, or is it worth reaching out to the study team directly to ask about my options?
4The main thing being measured is something called the Brief Pain Inventory — can my doctor explain what that tool actually captures, and whether the kind of pain I'm experiencing would even show up meaningfully in that kind of measurement?
5Before considering a study like this, should I first explore whether standard pain management options have been fully exhausted, or could this herbal patch approach be looked at alongside my current treatment plan?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Brief Pain Inventory - Measure of Participant Pain