CompletedNot Applicable

Antithrombin III and Post-liver Transplantation Acute Kidney Injury

South Korea2,395 participantsStarted 2010-01-04

Plain-language summary

The reno-protective effect of Antithrombin III (ATIII) has been well-studied in various animal studies; however, little is known about the effect of ATIII on kidney function in patients undergoing liver transplantation (LT). This study aimed to determine the association between preoperative ATIII level and postoperative acute kidney injury (AKI) after LT (post-LT AKI).

Who can participate

Age range19 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * patients who underwent either living- or deceased-donor LT (LDLT, DDLT) from January 2010 to January 2018 Exclusion Criteria: * patients who underwent re-transplantation * patients who were previously diagnosed with end-stage renal disease or Chronic kidney disease * patients who were being treated with continuous renal replacement therapy * preoperative or postoperative Antithrombin III levels were not available

What they're measuring

acute kidney injury

Timeframe: postoperative 7 day

Trial details

NCT IDNCT04912193

SponsorAsan Medical Center

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2019-01-31

View on ClinicalTrials.gov More Liver Transplantation and Antithrombin trials