Pulmonary Artery Doppler and Neonatal Outcome in Placenta Accreta Spectrum Patients (NCT04911322) | Clinical Trial Compass
CompletedNot Applicable
Pulmonary Artery Doppler and Neonatal Outcome in Placenta Accreta Spectrum Patients
Egypt71 participantsStarted 2021-08-15
Plain-language summary
To correlate ultrasonographic markers of fetal lung maturity including Pulmonary artery Doppler indices in the late preterm and early term in placenta accreta spectrum patients with neonatal outcome.
Who can participate
Age range18 Years – 42 Years
SexFEMALE
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Inclusion Criteria:
* Age: 18-42 years old
* Patients who will be diagnosed with placenta accreta spectrum preoperatively according to (ACOG 2018), (Jauniaux et al., 2018 a), (Jauniaux et al., 2018 b)
* Those who will undergo elective or emergency cesarean.
* With gestational age: 34 0/7 - 38 6/7 weeks
* Under the effect of general anesthesia
Exclusion Criteria:
* Multifetal pregnancy
* Intrauterine fetal death
* Intrauterine growth restriction (IUGR) which is defined as a rate of fetal growth that is less than normal for the growth potential of that specific infant
* Diabetes with pregnancy either gestational or overt which is defined as any degree of glucose intolerance with an onset or first recognition during pregnancy
* Pregnancy induced hypertension defined as either systolic blood pressure ≥ 140 mmHg or diastolic blood pressure ≥ 90 mmHg. It is classified as one of four conditions: preexisting hypertension, gestational hypertension, preeclampsia, preexisting hypertension with superimposed preeclampsia
* Premature rupture of membranes
* BMI above 40 due to technical difficulties to obtain accurate measures
* Narcotic usage during anesthesia before fetal delivery
* Major congenital fetal anomalies whether diagnosed before or after delivery
* Maternal fever more than 37.4 degree
* Emergent cases presenting with fetal distress (bradycardia will be defined as fetal heart rate \< 110 beat per minute)
* Patients who have not completed the course of antenatal corticosteroid…
What they're measuring
1
Acceleration time to ejection time (At/Et) ratio of fetal pulmonary artery Doppler in neonates with good and poor outcome.