RecruitingNot Applicable

Genetic Studies of Early-onset Dementia

United States1,000 participantsStarted 2016-09-14

Plain-language summary

The aim of this study is to identify genetic factors that contribute to risk and progression of early-onset dementia (loss of memory function before the age of 70 years) across all ethnic groups, including Alzheimer's Disease, mild cognitive impairment and other dementias.

Who can participate

Age range35 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria: * 35 years and older * Individuals experiencing memory concerns or diagnosed with dementia and their family members that are unrelated healthy controls without dementia. Exclusion Criteria: \- Individuals with competing diagnosis such as Huntington's disease, traumatic brain injury, drug or alcohol abuse, or schizophrenia, etc., unless family members of a dementia affected individual

What they're measuring

Genetic risk variants associated with early-onset dementia

Timeframe: 2 years

Changes in blood biomarkers in early-onset dementia

Timeframe: 2 years

Trial details

NCT IDNCT04906863

SponsorColumbia University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2028-04-30

Contact for this trial

Pamela Del Rosario

212-304-7284 pd2727@cumc.columbia.edu

View on ClinicalTrials.gov More Dementia, Early Onset trials