Cytokine Hemoadsorption in ECMO Patients (NCT04901338) | Clinical Trial Compass
CompletedNot Applicable
Cytokine Hemoadsorption in ECMO Patients
Slovenia25 participantsStarted 2017-06-01
Plain-language summary
Cytokine hemoadsorption is a novel therapy used to improve outcome in critically ill patients with a dysregulated cytokine response and hemodynamic instability. Patients on extracorporeal membraneous oxygenation (ECMO) often develop severe systemic inflammatory response syndrome (SIRS). Cytokine removal using different types of hemoadsorption devices is believed to block the vicious circle of inflammation dysregulation when other basic therapeutic measures fail. To date there are very limited reports on ECMO and cytokine hemoadsorption combination therapy. The aim of this retrospective study is to evaluate feasibility and effectiveness of hemoadsorption in veno-arterial and veno-venous ECMO patients.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* VA/VV ECMO
* hemoadsorption
* Age ≥ 18 years
Exclusion Criteria:
* no additional exclusion criteria after being eligible for ECMO
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial has already been completed — has the results data been published yet, and if so, what did it show about whether cytokine hemoadsorption actually helped stabilize blood pressure and circulation in ECMO patients?
2Since this study enrolled people with very serious conditions like cardiogenic shock, septic shock, and ARDS all on ECMO support, how sick would someone typically need to be to have been considered for something like this, and does that match my situation?
3The trial was listed as 'Phase NA,' which I understand means it wasn't a standard drug-testing phase — can you explain what that means for how much we can trust the safety and effectiveness findings from this kind of study?
4Cytokine hemoadsorption is a blood-filtering approach aimed at reducing the cytokine storm — are there already approved or standard treatments that do something similar, and how would you compare those options to what this trial was testing?
5Given that this trial focused specifically on ECMO patients, does being on ECMO or potentially needing ECMO change which treatment approaches you'd recommend for me, and is hemoadsorption something that's available outside of a research setting at this hospital?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.