Serum Based Diagnosis of and Monitoring of Infection Recovery in Orthopedic Spine Implant Infections

Inclusion Criteria: * patients with known or suspected spinal infections associated with spinal orthopedic implant(s); * patients over 18 years of age and younger than 85; * patients undergoing spinal revision surgery. Exclusion Criteria: * Diagnosed as immuno-compromised or immuno-suppressed based on medication use; * On-going or previously diagnosed musculoskeletal infections associated non-spine hardware (e.g., prosthetic hip, prosthetic knee, prosthetic shoulder); * Current diabetic foot ulcer/infection; * Patients undergoing cancer treatment (including radiation and chemotherapies); * Pregnancy; * Absence of a spleen; * Over the age of 85 or under the age of 18. * Weigh less than 110 pounds, or for which it would otherwise be unsafe for them to undergo a blood draw.