UnknownNot Applicable

Ex Vivo Study of the Mechanism of Action of Active Ingredients on the Intestinal Microbiota

4 participantsStarted 2021-09

Plain-language summary

To design and understand the mechanism of action of different combinations of nutraceuticals coupling bacteria, fibers and polyphenols, which can act on the 4 pillars simultaneously via an innovative ex-vivo model approach coupled with functional and quantitative metagenomics.

Who can participate

Age range18 Years – 60 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Person with a low fiber diet (\<17g / day). Exclusion Criteria: * Taking antibiotics and / or transit modulators in the 3 months preceding the sample; * Colonoscopy in the last 3 months; * Person under legal protection measure (curators, tutors, etc.).

What they're measuring

Bacterial growth

Timeframe: Day 1 to Day 15

PH evolution

Timeframe: Day 1 to Day 15

Quantity of Co2 production

Timeframe: Day 1 to Day 15

Trial details

NCT IDNCT04895774

SponsorNutri & Co

Sponsor typeINDUSTRY

Study typeOBSERVATIONAL

Primary completion2021-10

Contact for this trial

Hervé Blottière

06.19.32.28.72 herve.blottiere@inrae.fr

View on ClinicalTrials.gov More Microbial Colonization trials