CompletedPhase 3

18F-Fluorocholine Positron Emission Tomography (PET) for the Detection of Parathyroid Adenomas

United States139 participantsStarted 2021-06-30

Plain-language summary

This is a prospective single arm single center Phase III study evaluating the ability of 18F-fluorocholine to detect the location of parathyroid adenomas.

Who can participate

Age range13 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age \>= 13 years. * Biochemically proven hyperparathyroidism and an indication for surgery. * Ability to understand a written informed consent document, and the willingness to sign it. Exclusion Criteria: * Current Pregnancy. * Patients unlikely to comply with study procedures, restrictions and requirements and judged by the Investigator to be unsuitable for study participation.

What they're measuring

Proportion of participants with true-positives (sensitivity) of 18F-Fluorocholine PET using sestamibi imaging

Timeframe: Up to 1 year

Proportion of participants with true-positives (sensitivity) of 18F-Fluorocholine PET using predefined threshold

Timeframe: Up to 1 year

Trial details

NCT IDNCT04895631

SponsorThomas Hope

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-12-31

View on ClinicalTrials.gov More Hyperparathyroidism, Primary trials