The study will be carried out at the hospital of the medical school of sao paulo (HC-FMUSP) and the goal is to compare the effects of the administration of myo-inositol in relation to the effects of metformin in women with Polycystic Ovary Syndrome and insulin resistance or glucose intolerance. Menstrual cycle, hyperandrogenism, chronic inflammatory process, carbohydrate metabolism, hepatic steatosis will be evaluated. In total, 60 women in the reproductive period, with a variable age between 18 and 36 years old will be recruited and randomized in two groups: intervention- myo-inositol for 6 months, control group will use metformin also for 6 months.
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Menstrual cycle
Timeframe: 6 months
Change in glucose metabolism
Timeframe: Every 3 months for up to 6 months
Change in glycated hemoglobin
Timeframe: Every 3 months for up to 6 months
Change in ultrasound of the ovaries
Timeframe: 6 months
Change in antral follicle count
Timeframe: 6 months
Change in body mass index
Timeframe: Every 3 months for up to 6 months
Change in Abdominal Circumference and Hip Circumference
Timeframe: Every 3 months for up to 6 months
Change in body weight in kilograms
Timeframe: Every 3 months for up to 6 months