Testing the Effects of Exercise on Chemotherapy-Induced Peripheral Neuropathy

Inclusion Criteria: * Have a diagnosis of cancer * Have received neurotoxic chemotherapy within the past nine months (could still be on chemotherapy or have already completed chemotherapy; i.e., taxane-, platinum-, vinca alkaloid-, epothilone-, or proteasome inhibitor-based chemotherapy * Report one or more symptoms of CIPN at a level of \>= 4 on the CIPN symptom inventory on the Screening Form * Have an Eastern Cooperative Oncology Group (ECOG) performance status 0-1 * Have at least six months life expectancy * Be at least 18 years of age * Be able to read and understand English * Be able to provide written informed consent Exclusion Criteria: * Have physical limitations (e.g., cardiorespiratory, orthopedic, central nervous system) that contraindicate participation in a low to moderate intensity home-based walking and progressive resistance exercise program, according to the participant's physician (e.g., oncologist, primary care) or physician's designee * Be identified as in the active or maintenance stage of exercise behavior per the Exercise Stages of Change Question on the Screening Form * Have planned surgery or radiation treatment during the course of the study (hormonal and biologic therapy is allowed) * Have contraindications for MRI scanning, per the MRI safety screening procedures of the MRI facility to be utilized for this participant * Are pregnant of have plans to become pregnant during the course of the study. Documentation of pregnancy and use of contracept…