Narrow Band Imaging Bronchoscopy During SARS-CoV2 Infection (NCT04884061) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
Narrow Band Imaging Bronchoscopy During SARS-CoV2 Infection
France30 participantsStarted 2021-05-04
Plain-language summary
Vascular modifications have been described during SARS-CoV2 infection, especially a dilatation of the bronchial arteries. Within the airway wall, small branches of the bronchial arteries cross the muscle layer to develop a submucosal network. The Narrow Band Imaging technique is used during bronchoscopy to achieve a maximum contrast of vessels and the surrounding mucosa. Therefore, it enables to observe the microvessel structure and its distribution in the bronchial mucosa. The aim of this study is to describe the vasculature pattern of the bronchial tree during infection with SARS-CoV2.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients who undergo bronchoscopy with image and/or videos recording of NBI aspect of the proximal bronchial tree (carina, right and left upper lobe).
* Patients hospitalized with SARS-CoV2 infection proven by RT-PCR test
* patients hospitalized with lower respiratory tract infections unrelated to SARS-CoV2 (RT-PCR negative for SARS-CoV2)
* Patients who have had bronchoscopy performed as part of the assessment of a distal pulmonary nodule (RT-PCR negative for SARS-CoV2).
Exclusion Criteria:
* Patients under legal protection
* Patients who refuses the use of his personal medical data
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This study is using a special bronchoscopy technique called narrow-band imaging to look at blood vessel patterns in the airways of COVID-19 patients — can you explain what that procedure would actually involve for me, and what the risks of having a bronchoscopy are while I'm dealing with a COVID-19 infection?
2Since this trial is listed as 'active not recruiting,' does that mean I've missed the window to participate, and if so, are there similar studies looking at airway changes during COVID-19 that I might still be eligible for?
3The trial is comparing vasculature patterns across three different patient groups — can you tell me which group I would likely fall into, and what that means for what the researchers would be looking for in my case?
4This study doesn't appear to be testing a new treatment — it seems focused on observing and measuring airway changes — so would participating offer me any direct medical benefit, or would I mainly be contributing to research?
5Since this trial has no assigned phase, which usually means it's more of an observational or diagnostic study rather than a treatment trial, is there a standard-of-care approach to monitoring my airways during COVID-19 that might be worth discussing alongside or instead of this?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Variation of the vasculature pattern of the bronchial mucosa between the three patient groups