CompletedNot Applicable

Chronic Low Back Pain and Neck Pain Prospective Study

Hong Kong800 participantsStarted 2015-05-01

Plain-language summary

This prospective observation multifaceted study aims: 1. To perform a large prospective study and identify multiple "omics" biomarkers in chronic low back pain 2. To validate identified biomarkers for progression of acute to chronic low back pain 3. To validate identified biomarkers and test their heritability/validity in additional cohorts 4. To identify pathways and relevant individual variations for generation, propagation and subsidence of pain 5. To identify new imaging biomarkers related to chronic low back pain 6. To develop a registry of neck and low back pain subjects to help monitor the health-care management and utility to improve protocols and patient outcomes.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Neck and/or low back pain * New cases\* * Males and females * 18 years or older * Willing to participate in the study short- and long-term Exclusion Criteria: * Previous spine surgery * Cognitively impaired * Drug addiction * Incarceration (prisoner) * History of infections, tumors, chronic inflammation (e.g. rheumatoid arthritis, ankylosing spondylitis) * Congenital/syndromal * Pregnant females * Diagnosed psychological impairment * Inability to read or write

What they're measuring

Radiographic assessment

Timeframe: Change up to 60-months follow-up

MRI assessment

Timeframe: Change up to 60-months follow-up

Trial details

NCT IDNCT04883476

SponsorThe University of Hong Kong

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-06-30

View on ClinicalTrials.gov More Chronic Low Back Pain trials