A Randomized Trial Evaluating EARLY Application of a Surfactant Dressing in Thermal Injury (EARLY) (NCT04880655) | Clinical Trial Compass
CompletedNot Applicable
A Randomized Trial Evaluating EARLY Application of a Surfactant Dressing in Thermal Injury (EARLY)
United States27 participantsStarted 2021-08-03
Plain-language summary
The purpose of this study is to test the following hypotheses:
1. Early use of water-soluble surfactant dressing (WSD) on partial-thickness burn wounds will result in tissue salvage and reduce surgical burden.
2. Early use of WSD on partial-thickness burn wounds will result in faster healing.
3. Use of WSD on partial-thickness burn wounds will result in less painful wound care.
4. Early use of WSD on partial-thickness burn wounds will result in less infection.
5. Early use of WSD on partial-thickness burn wounds will result in lower hospital costs.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* age ≥ 18 years old
* admitted within 24 hours of injury
* partial-thickness burn wounds on at least two non-contiguous areas of \< 10% TBSA each and not involving face, fingers, toes, and perineum
* initial management assessed to require inpatient care
Exclusion Criteria:
* chemical, electrical, or inhalation injury
* pregnant
* incarcerated
* TBSA ≥ 20%
* wound expected to heal within 7 days
* patient or authorized representative unable or unwilling to consent
* unable to consent within 24 hours of injury
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial tested a surfactant dressing applied early to partial-thickness burns — can you explain what a surfactant dressing actually does to a burn wound, and how it might be different from what we're already using on my burn?
2The trial was measuring whether wounds 'converted' to a worse depth — what does wound conversion mean in my specific case, and how big a risk is it that my partial-thickness burn could get deeper without early treatment?
3Since this trial is already completed, have the results been published, and if so, do they suggest the surfactant dressing actually reduced wound conversion compared to standard care?
4This was listed as a 'Phase NA' study, which I take to mean it may not have followed the usual drug-trial safety phases — does that change how confident you are in the safety and effectiveness of this type of dressing for me?
5Even if I can't enroll since the trial is finished, is a surfactant dressing something you could consider using as part of my current treatment plan based on what's now known from this study?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Percent difference (cm2) in partial-thickness wound conversion