RecruitingNot Applicable

Wheat Beer for Prevention of Delirium in Intensive Care Patients

Switzerland380 participantsStarted 2023-01-18

Plain-language summary

The investigators hypothesise that the daily administration of 0.5L alcohol-containing wheat beer at 8 pm over a study period of 6 days in a row leads to a lower prevalence of delirium compared to water following the same administration scheme.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria All Patients meeting the following criteria are eligible for the study: * Risk of delirium: ICU patients with expected length of stay (LOS) ≥ 24 hours * Naso-gastric tube in situ * ICU stay ≤ 72h until first study intervention * Women: negative pregnancy test, age ≥50 years or status post hysterectomy/bilateral ovariectomy * Adult patients (age ≥ 18 years) * ≥ 50 kg body weight or BMI ≥18.5 Exclusion Criteria Patients fulfilling the following criteria are excluded from the study: * Pre-existing liver pathologies * Patients after bone marrow transplantation * Women: breastfeeding * Pre-existing delirium (ICDSC ≥ 4) * Terminal state * Active psychosis * Anamnestic complete alcohol abstinence or status post alcohol abuse * Especially vulnerable patients * Allergy to any ingredient(s) of beer

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Development of delirium

Timeframe: 7 days

Trial details

NCT IDNCT04876742

SponsorUniversity Hospital, Basel, Switzerland

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2028-12-31

View on ClinicalTrials.gov More ICU Delirium trials

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.