RecruitingNot Applicable

Dietary Intervention to Mitigate Adverse Consequences of Night Work

United States24 participantsStarted 2023-03-29

Plain-language summary

The goal of this clinical trial is to test whether our dietary intervention can prevent or lessen the negative health effects of night shift work in healthy participants. Participants will: * complete 2 inpatient stays * be provided with identical meals * have frequent blood draws * provide urine, saliva, stool and rectal swab samples

Who can participate

Age range18 Years – 45 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 18-45 yr old * BMI 20.0-29.9 * European/Hispanic/African-American ancestry * No acute, chronic or debilitating medical conditions (e.g. metabolic, cardiovascular, respiratory, neurological, cancers, etc.) Exclusion Criteria: * Currently smoking/vaping or 5 or more years of smoking/vaping * History of drug or alcohol dependency * History of psychiatric illness or disorder

What they're measuring

Change in glucose tolerance from Baseline to Test Day

Timeframe: Baseline (Day 2) and Test Day (Day 4)

Changes in microbial community structure/composition/function of oral and gut microbiome from Baseline to Test Day

Timeframe: Baseline (Day 2) and Test Day (Day 4)

Trial details

NCT IDNCT04868526

SponsorBrigham and Women's Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-09-01

Contact for this trial

Megan Munn

6175258259 mmunn@bwh.harvard.edu

View on ClinicalTrials.gov More Dietary Habits trials