UnknownNot Applicable

Uterine Natural Killer (uNK) Cell Expression in Patients With Repeated ICSI Failures: A Multicenter Cohort Study

Egypt120 participantsStarted 2021-05-01

Plain-language summary

uterine NK (uNK) cells are characterized by a high expression of CD56 (CD56brihgt), lack of CD16 expression, high secretion of cytokines and rather low cytotoxic activity. It has been shown that uNK cells increase in number during the late secretory phase and during early pregnancy. This study was designed to assess the possible role of uNK cells in repeated ICSI failure.

Who can participate

Age range20 Years – 40 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients with IVF/ICSI failures more than 2 times * Age 20-40 years Exclusion Criteria: * prior uterine surgery * immunological disease * previous testing to uNK cells

What they're measuring

Level of uNK cells

Timeframe: 4 months

Trial details

NCT IDNCT04867759

SponsorTanta University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2024-12-01

Contact for this trial

Ayman Dawoog, MD

+202020972067 ayman.dawood@med.tanta.edu.eg

View on ClinicalTrials.gov More Repeated Implantation Failure trials