CompletedNot Applicable

Internet-delivered Intervention Targeting Residual Cognitive Symptoms After Major Depressive Disorder

Norway44 participantsStarted 2021-04-26

Plain-language summary

Background: Cognitive impairment and difficulties are frequently observed in individuals suffering from major depressive disorder. These impairments and difficulties can persist into remission as residual cognitive symptoms. Consequently affecting daily life functioning and quality of life for those affected. Few scalable interventions have targeted these symptoms and measured long-term clinical effects such as depression relapse.

Who can participate

Age range

18 Years – 65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Previously received treatment for major depressive disorder in primary or secondary healthcare services * Reporting a history of major depressive disorder symptoms assess using the MINI. few or minor depression symptomss (\< 12 MADRS) * Not meeting criteria for major depressive disorder measured by the MINI) * Self-reporting residual cognitive symptoms that affects daily functioning (assessed by clinical psychologist) * No changes in anti-depressant medication under the study period * Age between 18 and 65 years * Read and write Norwegian * Internet and telephone access. Exclusion Criteria: * Self-reported substance abuse * Neurological conditions or damage (e.g. autism, cerebral haemorrhage, and brain tumour) * Bipolar disorder * Psychosis.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Behaviour Rating Inventory Of Executive Function-Adult

Timeframe: 2.5 years

Perceived Deficit Questionnaire 5

Timeframe: 2.5 years

Trial details

NCT IDNCT04864353

SponsorHaukeland University Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-10-31

View on ClinicalTrials.gov More Cognitive Remediation trials