The Effect of HIIT, MICT in Patients With Myocardial Infarction (NCT04863677) | Clinical Trial Compass
CompletedNot Applicable
The Effect of HIIT, MICT in Patients With Myocardial Infarction
China188 participantsStarted 2021-05-01
Plain-language summary
This study will investigate the effect of a 12-weeks cardiac rehabilitation training (HIIT, MICT) program on VO2peak and cardiac fibrosis in patients, and evaluate the effects of HIIT on endothelial function, microvascular obstruction, body fat, inflammation, arrhythmia and psychology .
Who can participate
Age range18 Years β 75 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
β. Aged 18 -75 years
β. Acute myocardial infarction (AMI) patients between 6 weeks and 3 months and had been underwent revascularization, and New York Heart Association functional classification (NYHA) Class I-III; (AMI confirmed by the World Health Organization definition (presence of symptoms of ischemia and changes in electrocardiogram) or the Third Universal Definition of Myocardial Infarction (elevation of a cardiac biomarker along with presence of either symptoms of myocardial infarction or changes in electrocardiogram))
β. Willing and able to attend the complete cardiac rehabilitation(CR)program on their ownοΌassigned the Informed consent form.
β. Complete the cardiopulmonary exercise testing (CPET) at enrollment or has the CPET report within 1 month.
Exclusion criteria
β. High-intensity exercise frequently
β. Currently participating in any other clinical trials
β. Have any other diseases which limit their life to less than a year (e.g. severe valvular disease, recurrent ventricular arrhythmias, NYHA Class IV heart failure, severe aortic incompetence, severe atrial fibrillation, cancers, and end-stage renal or liver disease)
β. Dementia ; disability or sports contraindication
β. Severe acute liver failure
β. Severe acute renal failure
β. Unstable vital signs
What they're measuring
1
The effect of HIIT/MICT on VO2peak
Timeframe: 3 months
2
Evaluate the degree of cardiac fibrosis in 3 groups by cardiac magnetic resonance