RecruitingNot Applicable

Longitudinal Impact of Stressors in Adults With Tourette Syndrome

United States140 participantsStarted 2021-09-30

Plain-language summary

The Investigators propose a two-year, longitudinal pilot study of TS adults (\>18) to determine impact of lifetime environmental stress exposure on tic severity, psychiatric comorbidity severity, and health-related quality of life (HRQOL).

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * adults (\>18) meeting Diagnostic and Statistics Manual, 5th edition (DSM-V) criteria for Tourette syndrome, chronic motor tic disorder, or chronic vocal tic disorder * ability to provide informed consent * English proficiency Exclusion Criteria: \- significant medical, neurologic, or psychiatric diagnoses (e.g. uncontrolled epilepsy, chronic heart failure, schizophrenia) besides TS and its commonly co-occurring psychiatric diagnoses

What they're measuring

Total Tic Score from Yale Global Tic Severity Scale (YGTSS)

Timeframe: 2 years post-baseline assessment

NeuroQOL-Depression Score

Timeframe: 2 years post-baseline assessment

Gilles de la Tourette Quality of Life Scale (GTS-QOL) Score

Timeframe: 2 years post-baseline assessment

Trial details

NCT IDNCT04851678

SponsorVanderbilt University Medical Center

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2027-03-01

Contact for this trial

Michelle Eckland, BS

615-875-7394 michelle.r.eckland.1@vumc.org

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