Up to 150 patients with hypersensitivity pneumonitis will be enrolled at 7 clinical centers across the United States. Patients will be followed for 24 months to determine if biomarkers in the blood can predict disease progression.
Age range
18 Years – 85 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Time to absolute FVC (percent predicted) decline ≥10 percent
Timeframe: Up to 24 months
Time to absolute DLCO (percent predicted) decline ≥10 percent
Timeframe: Up to 24 months
Time to relative FVC (percent predicted) decline ≥10 percent
Timeframe: Up to 24 months
Time to relative DLCO (percent predicted) decline ≥10 percent
Timeframe: Up to 24 months
Time to relative DLCO (percent predicted) decline ≥15 percent
Timeframe: Up to 24 months
Time to first adjudicated acute chronic hypersensitivity pneumonitis exacerbation
Timeframe: Up to 24 months
Need for a new course of oral or intravenous steroids
Timeframe: Up to 24 months
Time to death from any cause
Timeframe: Up to 24 months
Change from baseline in St. George's Respiratory Questionnaire total score at month 6
Timeframe: 6 months
Change from baseline in St. George's Respiratory Questionnaire total score at month 12
Timeframe: 12 months
Change from baseline in St. George's Respiratory Questionnaire total score at month 18
Timeframe: 18 months
Change from baseline in St. George's Respiratory Questionnaire total score at month 24
Timeframe: 24 months
Change from baseline in dyspnea using University of California San Diego Shortness of Breath Questionnaire at month 6
Timeframe: 6 months
Change from baseline in dyspnea using University of California San Diego Shortness of Breath Questionnaire at month 12
Timeframe: 12 months
Change from baseline in dyspnea using University of California San Diego Shortness of Breath Questionnaire at month 18
Timeframe: 18 months
Change from baseline in dyspnea using University of California San Diego Shortness of Breath Questionnaire at month 24
Timeframe: 24 months
Change from baseline in dyspnea using St. George's Respiratory Questionnaire symptoms score at month 6
Timeframe: 6 months
Change from baseline in dyspnea using St. George's Respiratory Questionnaire symptoms score at month 12
Timeframe: 12 months
Change from baseline in dyspnea using St. George's Respiratory Questionnaire symptoms score at month 18
Timeframe: 18 months
Change from baseline in dyspnea using St. George's Respiratory Questionnaire symptoms score at month 24
Timeframe: 24 months
Change from baseline in dyspnea using St. George's Respiratory Questionnaire activity score at month 6
Timeframe: 6 months
Change from baseline in dyspnea using St. George's Respiratory Questionnaire activity score at month 12
Timeframe: 12 months
Change from baseline in dyspnea using St. George's Respiratory Questionnaire activity score at month 18
Timeframe: 18 months
Change from baseline in dyspnea using St. George's Respiratory Questionnaire activity score at month 24
Timeframe: 24 months
Change from baseline in dyspnea using St. George's Respiratory Questionnaire impact score at month 6
Timeframe: 6 months
Change from baseline in dyspnea using St. George's Respiratory Questionnaire impact score at month 12
Timeframe: 12 months
Change from baseline in dyspnea using St. George's Respiratory Questionnaire impact score at month 18
Timeframe: 18 months
Change from baseline in dyspnea using St. George's Respiratory Questionnaire impact score at month 24
Timeframe: 24 months
Change from baseline in CT visual (≥10 percent) score at month 12
Timeframe: 12 months
Change from baseline in CT visual (≥10 percent) score at month 24
Timeframe: 24 months
Change from baseline in CT quantitative (≥3.4) score at month 12
Timeframe: 12 months
Change from baseline in CT quantitative (≥3.4) score at month 24
Timeframe: 24 months
Change from baseline in 6-min walk distance at month 6
Timeframe: 6 months
Change from baseline in 6-min walk distance at month 12
Timeframe: 12 months
Change from baseline in 6-min walk distance at month 18
Timeframe: 18 months
Change from baseline in 6-min walk distance at month 24
Timeframe: 24 months
Rate of decline in FVC (percent predicted) over 24 months
Timeframe: Up to 24 months
Rate of decline in FVC (ml) over 24 months
Timeframe: Up to 24 months
Rate of decline in DLCO (percent predicted) over 24 months
Timeframe: Up to 24 months
Rate of decline in DLCO (mmol/min/kpa) over 24 months
Timeframe: Up to 24 months