TerminatedNot Applicable

HFNC Vs LFNC in Patients with AF Undergoing RFCA Under Deep Sedation.

Stopped: Due to changes in logistics (indications Rf and attendance PFA), it has not been feasible to include the required number of participants in this study

Netherlands141 participantsStarted 2022-01-04

Plain-language summary

Oxygen supplementation through high flow nasal cannula (HFNC) may reduce the incidence of desaturation and hypoxemia during deep sedation at radiofrequency catheter ablation (RFCA procedures).This study is designed to test the hypothesis that the incidence of hypoxemia and desaturation in patients with atrial fibrillation undergoing RFCA under deep sedation, is less when using HFNC as compared to use of standard low flow nasal cannula (LFNC).

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adults undergoing an elective RFCA for atrial fibrillation in the Maastricht UMC Cardiac Catheter Labs under deep sedation administered by a clinician anesthesiology Exclusion Criteria: * Age under 18 years * Body Mass Index (BMI) \> 32 kg/m² * Diagnosed Sleep Apnoea Syndrome (SAS) * Chronic Pulmonary Obstructive Disease (COPD) gold IV and COPD gold III with frequent or recent exacerbation * Diagnosed pulmonary or cardiac condition requiring chronic oxygen therapy * Complete nasal obstruction * Active nose bleeding * Untreated pneumothorax (pre- existing) * Recent upper airway surgery * Recent base of skull fracture * Expected difficult airway

What they're measuring

Hypoxemia event

Timeframe: The outcome variable will be measured during the patient's sedation (0-4 hours).

Trial details

NCT IDNCT04842253

SponsorMaastricht University Medical Center

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-11-18

View on ClinicalTrials.gov More Deep Sedation trials