CompletedNot Applicable

Effect of H2 Receptor Antagonist and Proton Pump Inhibitor on the Positivity Rates and Clinical Outcomes of COVID-19

South Korea400,000 participantsStarted 2021-05-01

Plain-language summary

This retrospective cohort study aims to evaluate the effect of proton pump inhibitor (PPI) or histamine-2 receptor antagonist (H2RA) on the clinical outcomes and positivity rates of Coronavirus Disease-19 (COVID-19).

Who can participate

Age range18 Years

SexALL

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Inclusion Criteria: * Individuals who were tested for COVID-19 using real-time reverse transcriptase PCR assay of nasal and pharyngeal swabs Exclusion Criteria: * Record of a new prescription of non-steroidal anti-inflammatory drugs (NSAID) within 1 month of the test date * Patients who died within 48 hours after test.

What they're measuring

COVID-19 test positivity

Timeframe: Through test completion, an average of 1 day

Mortality

Timeframe: 60 days

Trial details

NCT IDNCT04834752

SponsorSeoul National University Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2021-12-31

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