CompletedNot Applicable

The Effects of Intermittent Hypoxic-hyperoxic Preconditioning for Patients Undergoing Cardiopulmonary Bypass.

Russia115 participantsStarted 2021-01-25

Plain-language summary

The aim of the study is to evaluate the effects of intermittent hypoxic-hyperoxic training (IHHT) to protect myocardium against perioperative myocardial injury during cardiac surgery using cardiopulmonary bypass.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Exclusion criteria

✕. Occlusive atherosclerotic disease of lower limbs,
✕. Acute coronary syndrome within 4 weeks before entry
✕. Preoperative renal insufficiency (serum creatinine higher than 200 mmol/L),
✕. Acute infectious diseases
✕. Partial and secondary generalized forms of epilepsy,
✕. Uncompensated hypertension (Blood pressure at the time of the procedure: systolic blood pressure more than 160 mm Hg, diastolic blood pressure more than 110 mm Hg)
✕. Severe bronchial asthma with the development of respiratory failure of the II-III degree and individual intolerance to oxygen deficiency.

What they're measuring

Death from a cardiac cause

Timeframe: The first 30 days from the date of discharge

Myocardial infarction

Timeframe: through study completion, an average of 1 month after discharge

Stroke

Timeframe: through study completion, an average of 1 month after discharge

Trial details

NCT IDNCT04833283

SponsorI.M. Sechenov First Moscow State Medical University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-05-15

View on ClinicalTrials.gov More Valvular Heart Disease trials