The Effects of Acute Melatonin Supplementation on Cardiovascular Responses to Sympathetic Activation

Inclusion Criteria: * Healthy men and women * Women must be premenopausal with a regular menstrual cycle (26-30 days) Exclusion Criteria: * History of autonomic dysfunction * Cardiovascular diseases * Diabetes * Tobacco/nicotine use * Systolic Pressure \>= 130 mmHg * Diastolic Pressure \>= 85 mmHg * Regular melatonin use \>= 1 use/week * Allergy to melatonin * Cardiometabolic medication use (e.g. anti-hypertensives, insulin-sensitizing, statins) * Sex hormone replacement medical use (e.g. testosterone, estrogen, progesterone) * Pregnancy