CompletedNot Applicable

Identifying Risk Factors for Developing AKI in Sepsis

United Kingdom300 participantsStarted 2021-03-15

Plain-language summary

A study to evaluate the prevalence of Acute Kidney Injury (AKI) in patients with Diabetic Ketoacidosis (DKA) and sepsis using data collected prospectively to a patient registry. The primary objective is to compare the prevalence of AKI in sepsis and DKA in different age groups in children and investigate the difference in the prevalence of hyperchloremia in the two groups.Secondary objectives are Compare the prevalence of AKI in sepsis and DKA in different age groups in children and investigate the difference in the prevalence of hyperchloremia in the two groups.

Who can participate

Age range0 Days – 18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria * Children under 16 years and admitted to PCCU or wards in the past 5 years * Diagnosis of DKA or Sepsis/severe bacterial infection/septic shock DKA - defined as per the British Society for Paediatric Endocrinology and Diabetes (BSPED) guidance. Sepsis is defined based on the International Pediatric Sepsis Consensus Conference guidance (2005) 8.3. Exclusion Criteria * Any patients identified as above but not able to obtain case notes for any reason. * Patients with pre-existing kidney conditions * Patients with inborn errors of metabolism

What they're measuring

Prevalence of Acute Kidney Injury in the sepsis and DKA cohorts

Timeframe: during admission to PICU

Trial details

NCT IDNCT04825639

SponsorCardiff and Vale University Health Board

Sponsor typeOTHER_GOV

Study typeOBSERVATIONAL

Primary completion2022-03-30

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