CompletedNot Applicable

Relationship Between Homocysteine and BMD

Spain760 participantsStarted 2019-04-01

Plain-language summary

The association between Homocysteine (Hcy) levels and bone mineral density (BMD) has been debated. Some studies have found a relationship between increased Hcy plasma levels and BMD in contrast; other studies have not found a relationship. The purpose of our study was to investigate whether or not Hcy plasma levels are related to BMD in a group of postmenopausal women.

Who can participate

Age range50 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Postmenopausal women * BMD measured by dual-energy X-ray absorptiometry (DXA) Exclusion Criteria: * Primary ovarian failure * Early menopause * Cardiovascular, liver, or renal diseases * Surgical menopause * History of cancer * Receiving treatment known to influence levels of Hcy or bone mineralization (folates or vitamin B12 supplements, menopausal hormonal treatment, corticosteroids, anticonvulsants, heparin, thiazide diuretics, and antiresorptive agents).

What they're measuring

BMD expressed in absolute values as g/cm2

Timeframe: one year before or after Homocysteine levels

Lumbar spine T-score

Timeframe: one year before or after Homocysteine levels

Femoral neck T-score

Timeframe: one year before or after Homocysteine levels

Total hip T-score

Timeframe: one year before or after Homocysteine levels

Trial details

NCT IDNCT04821492

SponsorFundación Santiago Dexeus Font

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2020-03-31

View on ClinicalTrials.gov More Postmenopausal Women trials