Safety and Efficacy of Low-intensity Shockwave Therapy for Peyronie's Disease

Inclusion Criteria: * ≥18 years old male, * Untreated Peyronie's disease (excepted oral therapy) (wash out: at least 1 month), * Single axis penile curvature in erection at 20 - 90 degrees at baseline, * Dorsal or lateral penile plaque, * Able and willing to perform ESWT self-treatment under supervision, * Able to understand and complete patient questionnaires, * Having sign an informed consent form prior to any study specific procedure, * Being covered by a national health insurance Exclusion Criteria: * Congenital penile deformity, * Hourglass deformity, * Circumferential plaque, * Septal or ventral plaque, * Plaque that cannot be palpated during clinical examination, * Previous intralesional injection for Peyronie's Disease, * Severe erectile dysfunction (EHS \< 3), * Current penile, malignancy, * Previous penile surgery except for circumcision or condyloma removal, * Previous pelvic radiation therapy, * Anti-coagulant medication, except acetylsalicylic acid up to 100mg daily, * Previous low-intensity focused shockwave therapy on penis, * Any other condition that would prevent the patient from completing the study, as judged by the principal investigator, * Being deprived of liberty or under guardianship.