Evaluation of Efficacy and Safety of Iloperidone in the Acute Treatment of Manic or Mixed Episodes Associated With Bipolar I Disorder

Inclusion Criteria: * Male or female patients 18 to 65 years of age (inclusive) * Diagnosed with bipolar I disorder, manic or mixed-type, per DSM-5 criteria * Voluntary hospitalization for current manic episode Exclusion Criteria: * Patients with a DSM-5 diagnosis of a psychiatric disorder other than bipolar I disorder that was the primary focus of treatment within the previous six months * Patients who are experiencing a first manic episode or meeting criteria for rapid cycling