UnknownNot Applicable

A Cognitive Bias Modification RCT for Aggression

United States45 participantsStarted 2021-05

Plain-language summary

This randomized controlled trial will test a computerized cognitive bias modification program (CBM) to treat attention and interpretive biases in patients with primary aggression.

Who can participate

Age range18 Years – 55 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Meet DSM-5 criteria for current IED, as assessed via phone screen and confirmed during an in-person diagnostic interview conducted during visit one of the study * Are able and willing to cooperate with study protocol; i.e. keep appointments, read and understand consent form, etc. * Have written and verbal English proficiency for understanding consent and study materials Exclusion Criteria: * Have a lifetime history of psychosis * Have current moderate to severe substance use disorder * Have a history of bipolar disorder * Have current major depressive disorder * Are younger than 18 or older than 55 years old * Are currently (past month) receiving treatment for anger or aggression * Recently (past month) started or changed psychotropic medications

What they're measuring

Change in a Aggression from pretreatment to end of treatment (4 weeks later) and 1-month follow-up

Timeframe: preatment, post-treatment (4 weeks later) and 1-month follow-up. Total of 2 months

Change in a Anger from pretreatment to end of treatment (4 weeks later) and 1-month follow-up

Timeframe: pretreatment, posttreatment (4 weeks later) and 1-month follow-up. Total of 2 months

Change in Social Information Processing from pretreatment to end of treatment (4 weeks later) and 1-month follow-up

Timeframe: pretreatment, posttreatment (4 weeks later) and 1-month follow-up. Total of 2 months

Trial details

NCT IDNCT04819230

SponsorTemple University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-05

View on ClinicalTrials.gov More Intermittent Explosive Disorder trials

Who can participate

Age range18 Years – 55 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Change in a Aggression from pretreatment to end of treatment (4 weeks later) and 1-month follow-up

Timeframe: preatment, post-treatment (4 weeks later) and 1-month follow-up. Total of 2 months

Change in a Anger from pretreatment to end of treatment (4 weeks later) and 1-month follow-up

Timeframe: pretreatment, posttreatment (4 weeks later) and 1-month follow-up. Total of 2 months

Change in Social Information Processing from pretreatment to end of treatment (4 weeks later) and 1-month follow-up

Timeframe: pretreatment, posttreatment (4 weeks later) and 1-month follow-up. Total of 2 months