Hematological Indices and Fecal Calprotectin Predict Histological Remission in Ulcerative Colitis (NCT04818788) | Clinical Trial Compass
UnknownNot Applicable
Hematological Indices and Fecal Calprotectin Predict Histological Remission in Ulcerative Colitis
24 participantsStarted 2021-04-01
Plain-language summary
Investigators aimed at investigating the prediction ability of faecal calprotectin to predict mucosal healing and histological remission in ulcerative colitis patients receiving biological therapy Investigators aimed to evaluate the prediction ability of NLR, PLR and MLR to predict mucosal healing and histological remission in ulcerative colitis patients receiving biological therapy.
Investigators evaluate the histological remission in ulcerative colitis patients receiving biological therapy in Assuit university hospital.
Who can participate
Age range
18 Years – 55 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* 24 patients (males and females at the age between 18 and 55 years) of ulcerative colitis indicated to biological therapy
Exclusion Criteria:
* \- Ulcerative colitis pregnant women
* Patient receiving biological therapy for extra intestinal manifestation
* Patients on corticosteroids more than 20 mg as it affects leucocytic count
* Patients under the age of 18 years
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Histological remission in ulcerative colitis patients receiving biological therapy
Timeframe: one year
2
Assessment of fecal calprotectin level in ulcerative colitis patients receiving biological therapy
Timeframe: one year
3
Assessment of the level of PLR, NLR , MLR in ulcerative colitis patients receiving biological therapy
Timeframe: one year
4
Ability of hematological indices and fecal calprotectin to predict histological remission