This phase II trial tests whether an exercise intervention works to improve cognitive function in breast cancer survivors. Many breast cancer survivors report cancer-related cognitive impairment, which this has recently become a priority in clinical research due to its dramatic impact on daily functioning, quality of life, and long-term health. Aerobic exercise has the potential to improve cognitive function and brain health in older adults and is recommended as a safe, tolerable, and accessible complementary therapy for breast cancer survivors. This study aims to understand the effects of physical activity compared with health education on memory, attention, and brain health in women with breast cancer. Study findings may help researchers design more programs that can improve memory, attention, and brain health in other women with breast cancer.
Age range
50 Years
Sex
FEMALE
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The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Change in inhibitory control
Timeframe: baseline (Month 0), post-intervention (month 6), follow up (month 12)
Change in cognitive flexibility
Timeframe: baseline (Month 0), post-intervention (month 6), follow up (month 12)
Change in executive function processing
Timeframe: baseline (Month 0), post-intervention (month 6), follow up (month 12)
Change in short-term memory
Timeframe: baseline (Month 0), post-intervention (month 6), follow up (month 12)
Change in verbal memory
Timeframe: baseline (Month 0), post-intervention (month 6), follow up (month 12)
Change in working memory
Timeframe: baseline (Month 0), post-intervention (month 6), follow up (month 12)
Change in brain volume
Timeframe: baseline (Month 0), post-intervention (month 6)
Change in white matter integrity
Timeframe: baseline (Month 0), post-intervention (month 6)
Change in resting state functional connectivity
Timeframe: baseline (Month 0), post-intervention (month 6)
Change in self-reported cognitive function
Timeframe: baseline (Month 0), post-intervention (month 6), follow up (month 12)
Reach
Timeframe: baseline (Month 0)
Adoption
Timeframe: post-intervention (month 6)
Change in Cardiorespiratory Fitness
Timeframe: baseline (Month 0), post-intervention (month 6), follow up (month 12)
Change in Cancer-related Fatigue
Timeframe: baseline (Month 0), post-intervention (month 6), follow up (month 12)
Implementation
Timeframe: post-intervention (month 6)
Maintenance
Timeframe: follow up (month 12)
Change in processing speed
Timeframe: baseline (Month 0), post-intervention (month 6), follow up (month 12)
Change in attention
Timeframe: baseline (Month 0), post-intervention (month 6), follow up (month 12)