CompletedNot Applicable

Pre-op Cognitive Behavior Therapy to Decrease Chronic Post-Surgical Pain in TKA

United States54 participantsStarted 2020-10-01

Plain-language summary

A significant number of patients develop chronic post-surgical pain (CPSP) following knee replacement surgery. Proposed is the testing of a novel computer-assisted behavioral intervention integrating motivational interviewing in the 4 weeks prior to surgery to address the risk factors for CPSP, with the expectation that severity of post-op pain and the incidence of CPSP will be reduced.

Who can participate

Age range22 Years

SexALL

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Inclusion criteria

✓. Males and females, age \> 21 years
✓. Chronic non-malignant pain of at least 3 months duration
✓. Morphine equivalent daily dose (MEDD) \> 40 milligrams for at least 3 months
✓. Able to enroll at least 4 weeks prior to planned surgery
✓. Able to speak, read and comprehend in English at the 6th grade or higher proficiency

Exclusion criteria

✕. Pain of malignant origin
✕. Current or past history of opioid use disorder (including those on medication-assisted therapy)
✕. Revision of TKA
✕. Comorbid CNS disease such as dementia, HIV, psychosis, poorly controlled bipolar disorder or any condition interfering with informed consent

What they're measuring

Preoperative Chronic Pain Severity

Timeframe: prior to surgery, approximately 6 weeks following baseline.

Trial details

NCT IDNCT04814992

SponsorUniversity of Pennsylvania

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-12-31

Results submitted2024-01-23

View on ClinicalTrials.gov More Chronic Post-Surgical Pain trials