Use of proton pump inhibitors (PPI) has increased in recent years. There are concerns that PPIs have possible negative effects on bone metabolism. It has been suggested that PPIs may reduce the absorption of calcium from the small intestine and lead to bone resorption by affecting osteoclastic activity. In this study, it is planned to investigate the effects of lansoprazole, a proton pump inhibitor, on bone turnover markers in pediatric patients with gastroesophageal reflux or gastroesophageal reflux disease.
Age range
16 Years – 18 Years
Sex
ALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Measuring serum calcium levels
Timeframe: First day
Measuring serum alkaline phosphatase levels
Timeframe: First day
Measuring serum magnesium levels
Timeframe: First day
Measuring serum osteocalcin levels
Timeframe: First day
Measuring serum parathyroid hormone levels
Timeframe: First day
Measuring serum vitamin D levels
Timeframe: First day
Measuring urine deoxypyridinoline levels
Timeframe: First day
Measuring spot urine calcium levels
Timeframe: First day
Measuring urine creatinine levels
Timeframe: First day
Measuring urine C-terminal telopeptides Type I collagen levels
Timeframe: First day
Measuring urine N-terminal telopeptides Type I collagen levels
Timeframe: First day