Use of proton pump inhibitors (PPI) has increased in recent years. There are concerns that PPIs have possible negative effects on bone metabolism. It has been suggested that PPIs may reduce the absorption of calcium from the small intestine and lead to bone resorption by affecting osteoclastic activity. In this study, it is planned to investigate the effects of lansoprazole, a proton pump inhibitor, on bone turnover markers in pediatric patients with gastroesophageal reflux or gastroesophageal reflux disease.
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Measuring serum calcium levels
Timeframe: First day
Measuring serum alkaline phosphatase levels
Timeframe: First day
Measuring serum magnesium levels
Timeframe: First day
Measuring serum osteocalcin levels
Timeframe: First day
Measuring serum parathyroid hormone levels
Timeframe: First day
Measuring serum vitamin D levels
Timeframe: First day
Measuring urine deoxypyridinoline levels
Timeframe: First day
Measuring spot urine calcium levels
Timeframe: First day
Measuring urine creatinine levels
Timeframe: First day
Measuring urine C-terminal telopeptides Type I collagen levels
Timeframe: First day
Measuring urine N-terminal telopeptides Type I collagen levels
Timeframe: First day