The randomized controlled trial is aimed to study the efficacy of virtual reality (VR) and its impact on upper limb function and postural stability in people with mild to severe multiple sclerosis (pwMS). The conceptual idea is to compare two kinds of neuroproprioceptive "facilitation and inhibition" physical therapy, first in a real environment and second in virtual reality, in out-patient therapy that will be held in 15 hourly therapies, 2x a week in a period of two months. The efficacy will be assessed by a blinded independent clinical examiner using clinical examination and questionnaire survey before and in a week following the therapeutic intervention. The main focus is on upper limb gross and fine motor skills, trunk stability and stability, and sit to stand stability.
Age range
18 Years – 75 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Nine Hole Peg Test (9HPT) - change pre/post intervention
Timeframe: Pre-assessment (baseline testing), Post-assessment (immediately in a week following the last procedure)
Box and Block Test (BNB) - change pre/post intervention
Timeframe: Pre-assessment (baseline testing), Post-assessment (immediately in a week following the last procedure)
Hand Grip Strength (HGS) -change pre/post intervention
Timeframe: Pre-assessment (baseline testing), Post-assessment (immediately in a week following the last procedure)
Tremor; Frequency for which the smoothed power spectral density is maximal (fMAX)
Timeframe: Pre-assessment (baseline testing), Post-assessment (immediately in a week following the last procedure)
Tremor; Power of the signal in band from f1 to f2 (Pf1-f2)
Timeframe: Pre-assessment (baseline testing), Post-assessment (immediately in a week following the last procedure)
Five times Sit to Stand test (5STS) -change pre/post intervention
Timeframe: Pre-assessment (baseline testing), Post-assessment (immediately in a week following the last procedure)