CompletedNot Applicable

Tube Feeding in Children Having a Bone Marrow Transplant

United Kingdom43 participantsStarted 2021-03-15

Plain-language summary

The purpose of this study is to assess the problems and a range of nutritional and clinical outcomes that occur with two feeding tubes used by children having a bone marrow transplant. Children and parents will also be interviewed to ask about their experiences of tube feeding.

Who can participate

Age range1 Month – 13 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Admitted to the centre during the study period for an allogeneic bone marrow transplant (BMT) for any diagnosis. * Receiving any conditioning regimen, donor type and stem cell source. * Children admitted for their second or more BMT. * Children admitted on an established enteral tube feeding regimen. * NHS patients. Exclusion Criteria: * Children receiving first-line, prophylactic, parenteral nutrition as this is not the standard nutrition pathway of most children receiving BMT at the centre. This is usually given in specific circumstances such as children receiving cord blood transplants or those with gastrointestinal diseases. * Autologous BMT, including children receiving chimeric antigen receptor T-cell therapy (CAR-T). * No feeding tube placed and no nutrition support required from tube feeding or parenteral nutrition. Children rarely do not require any form of nutrition support.

What they're measuring

Weight Z-score

Timeframe: Measured weekly for six weeks from admission for bone marrow transplant, and monthly thereafter to six months post-transplant (6 months)

Trial details

NCT IDNCT04804631

SponsorInstitute of Child Health

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2023-05-01

View on ClinicalTrials.gov More Bone Marrow Disease trials