Vitamin E Dosing Study

Inclusion Criteria: * 18 years of age or older as of the initial screening interview and provision of consent * FibroScan CAP\>280 dB/m within 60 days prior to randomization. * ALT ≥ 60 U/L within 30 days of randomization Exclusion Criteria: * Concurrent or prior use (within 90 days) of vitamin E supplements in excess of 40 IU/day * Current or history of significant alcohol consumption for a period of more than 3 consecutive months within 1 year prior to screening (significant alcohol consumption is defined as more than 20 g/day (\~1.5 drinks/day) (\> 10.5 drinks per week) in females and more than 30 g/day (\~2 drinks/day) (\>14 drinks per week) in males, respectively. One "standard" drink (or one alcoholic drink equivalent) contains roughly 14 grams of pure alcohol, which is found in: 12 ounces of regular beer, 5 ounces of wine, or 1.5 ounces of distilled spirits). * Inability to reliably quantify alcohol consumption based upon local study physician judgment * Continued use of drugs historically associated with NAFLD (amiodarone, methotrexate, systemic glucocorticoids, tetracyclines, tamoxifen, estrogens at doses greater than those used for hormone replacement, anabolic steroids, valproic acid, and other known hepatotoxins) for more than 2 weeks in the 6 months prior to randomization * Current use of anticoagulation therapy (not including antiplatelet agents such as aspirin or clopidogrel) * Platelet count below 150,000 /mm3 within 90 days of randomization * History of co…