CompletedPhase 4

Long-pulsed 1064 nm Nd-YAG Laser Versus TCA 20% in Treatment of Keratosis Pilaris

Egypt20 participantsStarted 2021-03-17

Plain-language summary

Keratosis pilaris (KP) is a common disorder of keratinization. There are different treatment modalities for KP with variable results. Nd:YAG laser and chemical peels are among these treatment modalities, however, there is no enough evidence in the literature regarding their efficacy. The aim of this study is to assess and compare the efficacy of long pulsed Nd:YAG laser and trichloreacetic acid 20% in treatment of keratosis pilaris.

Who can participate

Age range

18 Years – 60 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients above 18 years with KP. * Patients with KP affecting back of the trunk, arms, thighs, forearms, legs and buttocks. Exclusion Criteria: * Pregnant or lactating females. * Patients who had performed any laser treatment for KP within 6 months prior to the study. * Patients with history of oral retinoids within 3 months prior to the study. * Patients with history of hypertrophic scars or keloids. * Patients who used any topical treatment one month prior to the session. * Patients with acne affecting the same sites of keratosis pilaris. * Patients with active skin diseases affecting the area involved with KP e.g. folliculitis and eczema.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change of clinical and dermoscopic scores of KP with Nd-YAG laser

Timeframe: 4 months

Change of clinical and dermoscopic scores of KP with TCA 20%

Timeframe: 4 months

Trial details

NCT IDNCT04797663

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-07-18

View on ClinicalTrials.gov More Keratosis Pilaris trials