Comparison of an Opioid-Free Anesthesia Protocol Versus Standard Practices on Early and Late Post-operative Recovery

Inclusion Criteria: * Age \> 18 years * Surgery lasting more than 90 minutes with planned use of morphine analgesics during post-operative hospitalization (outside the PACU stay), * ENT surgery, plastic and reconstructive surgery, digestive and visceral surgery, urological surgery and gynecological surgery, * Surgery that does not involve any bone procedure, * Written consent of the patient, * French-speaking patient, able to understand and answer a questionnaire, * Social security affiliation Exclusion Criteria: * Pregnant, breastfeeding or parturient woman, * Person deprived of liberty by judicial or administrative decision, * A person who is subject to a legal protection measure, * Person unable to express consent, * BMI \< 18 and \> 39 kg/m2, * Drug contraindications, in particular hypersensitivity to the active substances of one of the study drugs (in particular lidocaine hydrochloride or amide- or clonidine-linked local anaesthetics) or to one of the excipients, * Porphyria, * Heart failure or unstable coronary artery disease, * bradyarrhythmia due to sinus node disease or conduction clock, or Adam-Stock's syndrome, not fitted, * Hepatocellular insufficiency with TP \< or =50%, * Chronic renal failure with glomerular filtration \< 60 ml/min. * Long-term treatment with Imipraminics, Neuroleptics, Baclofen, and all other molecules at risk of QT prolongation, * Uncontrolled epilepsy, * Chronic treatment with beta-blockers, * Need for induction in fast sequence, * Severe…