CompletedNot Applicable

The Effects of Fish Oil Supplementation on the Brain Health of Collegiate Football Athletes

United States38 participantsStarted 2019-05-28

Plain-language summary

Determine if the daily docosahexaenoic acid (DHA)/eicosapentaenoic acid (EPA) supplement will reduce serum levels of biomarkers of sub-concussion injuries over a course of American football season among collegiate football athletes.

Who can participate

Age range18 Years – 25 Years

SexMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Exclusion criteria

✕. Chronic daily anti-inflammatory drugs (\>20 d).
✕. Medications for blood lipids.
✕. Active fish oil or omega-3 fatty acid supplementation.
✕. Consumption of more than two servings of fish per week.
✕. Injured and unable to participate in regularly schedule conditioning or competitions.
✕. Acute concussion experienced within 30 days of starting the study.
✕. Fish allergies.

What they're measuring

Changes in Brain Biomarkers Due to Sub-concussion Injury - Nf-L

Timeframe: Baseline, Week 17, Week 26

Changes in Sub-concussion Injury Related Inflammation Biomarkers - TNF-α

Timeframe: Baseline ans Week 26

Changes in Sub-concussion Injury Related Inflammation Biomarkers - IL-6

Timeframe: Baseline; Week 17; Week 26

Trial details

NCT IDNCT04796207

SponsorUniversity of Arizona

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2020-01-28

Results submitted2025-03-26

View on ClinicalTrials.gov More Traumatic Brain Injury (TBI) trials