CompletedNot Applicable

Is Involucrin Has a Role in Verruca Vulgaris? A Clinical and Immunohistochemical Study

Egypt60 participantsStarted 2019-01-01

Plain-language summary

Vitamin D3 plays important role in keratinocyte differentiation and had been used recently in verruca vulgaris. Aim of the work: To assess the expression of involucrin in verrucae vulgaris before and after injection of vitamin D3. Subjects and Methods: This study included 60 patients with verrucae vulgaris subjected to intralesional injection of vitamin D3 at three weeks interval for a maximum of five sessions. Immunohistochemical assessment of involucrin was done before and after injection and compared to skin biopsies from 30 healthy individuals

Who can participate

Age range18 Years – 45 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria: Patients with multiple verruca vulgaris Patients with with verrucae vulgaris with size more than 3 cm Exclusion Criteria: Patients with a past history of allergic response to vitamin D. Pregnant or lactating females. Hepatic patients. Renal patients. Patients with bleeding tendency.

What they're measuring

Resolution of verrucae

Timeframe: 3 months

Trial details

NCT IDNCT04793529

SponsorBenha University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-10-01

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