UnknownPhase 4

Kefazolin Versus Kefazolin Plus Metronidazole to Reduce Postpartum Infection

South Africa1,000 participantsStarted 2021-03-08

Plain-language summary

Randomised controlled trial to investigate the efficacy of adding metronidazole pre-operatively to kefazolin in reducing postpartum infection

Who can participate

Age range18 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: 18 years and older Willing and able to provide written informed consent Exclusion Criteria: * women younger than 18 years women not able or willing to provide written informed consent women with or without infection already receiving antibiotics for other indications women allergic to kefazolin or metronidazole

What they're measuring

Efficacy of reducing surgical site infection

Timeframe: Seven days post-operatively

Trial details

NCT IDNCT04792710

SponsorUniversity of Pretoria

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-03-31

Contact for this trial

Leon C Snyman, PhD

+27834621818 leon.snyman@up.ac.za

View on ClinicalTrials.gov More Prevention of Postpartum Sepsis trials