CompletedNot Applicable

Cognitive Fitness for Depression in Older Adults

United States38 participantsStarted 2020-11-15

Plain-language summary

This research is being done to determine if computerized administered cognitive fitness activities will improve thinking and depression in older depressed adults who are being treated with antidepressants. The investigators are also interested in whether participating in the treatment will result in changes to brain activity measured with magnetic resonance imaging (MRI).

Who can participate

Age range60 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * ability to read and write in English * current major or mild depression despite ongoing treatment * under the care of a physician who prescribes medication for depression * currently treated with an antidepressant for at least 8 weeks Exclusion Criteria: * psychosis * other psychiatric disorders (except personality \& generalized anxiety disorders) * substance use disorders in the prior year * clinical diagnosis of dementia * neurological disorders (e.g., stroke, epilepsy, brain injury with loss of consciousness \> 30 minutes, brain tumors, demyelinating diseases) * corrected visual acuity \< 20/70 or color blindness

What they're measuring

Trail Making Part B Test

Timeframe: Pre-treatment and six weeks later when treatment has ended

Montgomery Asberg Depression Rating Scale (MADRS)

Timeframe: Pre-treatment and six weeks later when treatment has ended

Trial details

NCT IDNCT04790630

SponsorUConn Health

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-10-15

Results submitted2026-03-18

View on ClinicalTrials.gov More Depression Mild trials