Distribution and Clinical Implication of CMD in Patients With HFpEF Without Significant CAD

Inclusion Criteria: * Subject must be at least 19 years of age. * Subject with preserved ejection fraction (ejection fraction \> 50%) * Subject presented with dyspnea on exertion (NYHA Grade 2 or more) and diagnosed as HFpEF using HFA-PEFF scoring system (HFA-PEFF ≥5 or 2-4 with abnormal stress test or invasive hemodynamic test) * Subject who clinically need coronary angiography * Subject who is able to voluntarily sign informed consent form Exclusion Criteria: * Subject with reduced ejection fraction (\<50%) * Subject with significant coronary artery stenosis on coronary angiography (diameter stenosis ≥90% or 50-90% with fractional flow reserve \[FFR\] ≤0.80) * Subject who has other obvious causes of dyspnea (ex, lung disease) * Subject who have non-cardiac co-morbid conditions with life expectancy \<1 year