Cryoneurolysis Outcome on Pain Experience (COPE) in Patients With Low-back Pain

Inclusion Criteria: * Low-back pain from facet joint syndrom (facet joint pain) \> 3 months' duration with or without neuropathic pain component. * Low-back pain on Numeric Rating Scale ≥ 4 Exclusion Criteria: * Presence of nerve root or spinal canal compression; signs of inflammatory or erosive processes in the spine verified on magnetic resonance imaging (MRI). * Neurological deficits i.e. symptoms of nerve root compression; tingling, numbness, weakness/ paresis, and reflex loss in the lower extremities. * Major co-morbidity. * Anti-thrombotic or anti-platelet treatment which cannot be paused for a week. * Active malignancies. * Chronic inflammatory disease. * Known severe psychiatric disease. Patients with mild and well-treated depression and anxiety are not excluded.