Active — Not RecruitingNot Applicable

ATOMIC (Active Teens Multiple Sclerosis) Physical Activity Research Program

United States, Canada56 participantsStarted 2020-12-01

Plain-language summary

The investigators have previously shown that youth with MS are very inactive, and that vigorous physical activity is associated with higher levels of well-being and lower MS disease activity in youth. Yet, no effective physical activity interventions have been developed for youth with MS to date. The investigators have taken input from youth with MS to create a Smartphone-based app (the ATOMIC - Active Teens with Multiple Sclerosis - App) that provides tailored physical activity information and coaching, provides tools to increase social connectedness, and promotes physical activity. This proposed research will therefore address the problem of inactivity in youth with MS by studying an intervention to increase physical activity.

Who can participate

Age range11 Years – 21 Years

SexALL

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Inclusion criteria

✓. Youth 11-21 years of age;
✓. MS diagnosis or clinically isolated syndrome, as per revised McDonald diagnostic criteria and International Pediatric MS Study Group criteria prior to the age of 18;
✓. Participating in less than three hours of structured physical activity per week.

Exclusion criteria

✕. Have non-specific white matter abnormalities and metabolic or infectious etiologies for white matter abnormalities;
✕. Do not speak and read English at a level needed to complete the questionnaires (4th grade level);
✕. Have significant motor disability, classified as an Expanded Disability Status Scale (EDSS) ≥4;
✕. Are at increased risk of cardiac or other complications of exercise testing (e.g. cardiac disease, diabetes), as determined by the pediatric neurologist or physician.

What they're measuring

Physical Activity Level

Timeframe: Entire study - up to 18 months

Trial details

NCT IDNCT04782466

SponsorThe Hospital for Sick Children

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-09

View on ClinicalTrials.gov More Pediatric Multiple Sclerosis trials