CompletedNot Applicable

Bergen Oral Respiratory Intervention Study

Norway62 participantsStarted 2021-04-27

Plain-language summary

The purpose of this study is to investigate if treatment of periodontitis (gum disease) in a relatively young and healthy population can improve lung function. It is hypothesized that removing the dental biofilm reduce the source of inflammatory bacteria that can reach the lungs, and thereby reduce lung inflammation and lead to improved lung function.

Who can participate

Age range25 Years – 45 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * clinical diagnosis of periodontitis (stadium I or II) * measures of periodontal infection (PI) \> 50% * inflammation (bleeding index/bleeding on probing) \> 50% * never-smoker Exclusion Criteria: * asthma * symptoms of pollen allergy * chronic lung diseases * daily medication use which may interfere with the evaluation of the subject * pregnancy * use of systemic antibiotics last six months * subgingival scaling last six months * regularly use of oral antiseptic mouth rinse * use of snus (moist/smokeless tobacco) * current medical condition which may interfere with the evaluation of the subject

What they're measuring

Forced Vital Capacity (FVC) (L)

Timeframe: Baseline, 3 weeks, 6 weeks, 3 months, 6 months, 9 months and 12 months

Forced Expiratory Volume in one second (FEV1) (L)

Timeframe: Baseline, 3 weeks, 6 weeks, 3 months, 6 months, 9 months and 12 months

Forced Oscillation Technique (FOT)

Timeframe: Baseline, 3 weeks, 6 weeks, 3 months, 6 months, 9 months and 12 months

Trial details

NCT IDNCT04781153

SponsorAnders Røsland

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-06-27

View on ClinicalTrials.gov More Periodontitis trials