CompletedPhase 4

Effectiveness of Mineral Trioxide Aggregate and Platelet Rich Fibrin Along With Biodentine. .

India60 participantsStarted 2020-02-01

Plain-language summary

The aim of this study was to clinically and radiographically evaluate the effectiveness of MTA, Biodentine, Platelet Rich Fibrin along with Mineral Trioxide Aggregate and Platelet Rich Fibrin along with Biodentine as pulpotomy medicament in patients with pulpitis.

Who can participate

Age range

20 Years – 55 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients with carious exposed tooth exhibiting clinical and radiographical evidence for pulpitis. * Deep caries extending ≥2/3 of dentin. * Tooth with positive response with cold testing. * Tooth with no mobility. * No signs of pulpal necrosis including sinus tract or swelling. * Patient approval for the treatment and follow up Exclusion Criteria: * Any systemic disease that could influence the outcome. * Non-restorable tooth. * Teeth with periapical widening. * Tooth which cannot be isolated. * Teeth with marginal periodontitis or crestal bone loss. * Indication of post/ post and core restoration marginal periodontitis with attachment loss \>5mm. * Teeth with immature root or calcified canal. * Teeth with internal and external resorption. * No pulp exposure after caries excavation. * Uncontrolled bleeding after access cavity preparation after several minutes N * No bleeding at all at the time of access opening * Pregnant or nursing women. * Individual hypersensitive or allergic to any product used in the study

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

EPT

Timeframe: change from baseline to 1day, 3 months, 6 months, 9 months

cold test

Timeframe: change from baseline to 1day, 3 months, 6 months, 9 months

Trial details

NCT IDNCT04773886

SponsorMaharishi Markendeswar University (Deemed to be University)

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-03-12

View on ClinicalTrials.gov More Pulpitis - Irreversible trials

Who can participate

Age range

20 Years – 55 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.