UnknownNot Applicable

Comparison of Posterior Ocular Changes Between Singleton Pregnancy and Multifetal Pregnancy.

Thailand166 participantsStarted 2021-09-03

Plain-language summary

It has been known that a pregnant women undergoes significant anatomical and physiological changes that mainly caused by hormonal and hematologic changes during pregnancy. Due to advance in reproductive medicine, the incidence of multifetal pregnancy was increased to 3% of livebirth. Multifetal pregnancies produce much more physiological changes in the body compared to the singleton pregnancies. Physiologic ocular changes during pregnancy are the followings * Melanogenesis of eyelid and facial skin * Cellular alteration of lacrimal and meibomian gland * Increased corneal thickness and corneal curvature * Increased lens thickness * Increased retinal vascular density * Increased choroidal thickness Decreased intraocular pressure -

Who can participate

Age range24 Years – 37 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 24-37 years * 30-36 weeks of gestational age * clear ocular media * written informed consent Exclusion Criteria: * high risk pregnancies such as pre-eclampsia, gestational diabetic mellitus and asthma * history of refractive error, spherical equivalent \> 3 diopters * history of retinal diseases such as central serous chorioretinopathy and retinal vascular occlusion * history of intraocular inflammation or endophthalmitis * history of intraocular laser treatment * history of intraocular surgery

What they're measuring

Choroidal thickness

Timeframe: 30-36 weeks of gestational age

Trial details

NCT IDNCT04773561

SponsorKhon Kaen University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-12-30

Contact for this trial

Suthasinee Sinawat, MD

+66815454594 ssuthasinee@kku.ac.th